PHRM 211 Lecture 28: CARD Arrhythmia Therapeutics (Part 3)
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Contraindications: >80 yo, unstable angina/mi in past 6 months, hf nyha class ii. 1 mg iv over 10 min , repeat x 1 if needed. Contraindications: hx of torsades de pointes, qtc >440 ms, unstable hf, acs/cabg in past 6 months, monitor ecg x 4 hours in ed. 3 mg/kg iv over 10 mins , 2 mg/kg iv repeat. Contraindications: sbp <100 mmhg, qtc >440 ms, acs in past 30 days, nyha hf. Class ii/iv, monitor ecg x 2 hours in ed, non-formulary. High-dose iv or oral amiodarone may convert af, but conventional doses do not. Oral sotalol is not effective for acute conversion. convert af to nsr quickly in the acute setting. Both amiodarone and sotalol are effective for maintenance of nsr. Af episodes lasting < 48h, or after negative clot on acute tee (if not taking oac) First episode or paroxysmal af (new onset), not persistent or permanent af (chronic)
