KINE 2011 Chapter Notes - Chapter 1.8: Globular Protein, Cytoskeleton, Complex Cell
29 Oct 2017
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Cytoskeleton: cytoskeleton is complex network of protein in cytoplasm that provides cell shape, support & movement of components, elements of cytoskeleton, microtubules, microfilaments, intermediate filaments. Transport of secretory vesicles: microtubules provide highways for vesicular traffic along axon, molecular motor is a protein that attaches to particle to be transported & uses energy from atp to walk along microtubule, kinesin is a molecular motor. Consists of 2 globular heads, a stalk & tail. Kinesin tail binds to secretory vesicle & globular heads act like feet too move along microtubule. Kinesin carries cargo: dynein is motor that carries debris containing vesicles which are carried to lysosomes. Have 9+2 structure- 9 fused pairs (doublet) of microtubules arranged in an outer ring around 2 single unfused microtubules: basal body is where the cilium & flagellum originates. Formation of mitotic spindle: replicated chromosomes are pulled apart my mitotic spindles, which assemble only during cell division, microtubules are formed by centrioles.
