KINE 2011 Lecture Notes - Lecture 6: Renal Artery, Intermediate Filament, Keratin
17 Sep 2017
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Microtubules: protein subunit = tubulin (two types, alpha and beta). Larger of the three (diameter of 25 nm). Forms main component of cilia, flagella and mitotic spindle (cell division) Two-way vesicular axonal transport facilitated by microtubular highway . Kinesin moves vesicles towards outsides of cell (e. g. exocytosis) Dynein moves vesicles towards inside of cell (e. g. endocytosis) Dynamic because the cell can grow them, restructure them as needed. Example cells of respiratory tract use cilia to sweep particles up and out of airways. You generally only have one in the cell (in. Microtubules in these cilia and flagella provide structure, shape and support. Can transport organelles via highways" as well. Interconnection between cytoskeletal structure and organelles: microfilaments: are involved in cellular contraction. They also help make the contractile ring during cell division (when the cell needs to split). Four cell tupes that move on their own: White blood cells (via complex microfilament actin-based assemblies)
