BIO230H1 Chapter Notes - Chapter 3: Carry Out, Positive Feedback, Skeletal Muscle
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BIO230H1 Full Course Notes
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Bio230 lecture 3 readings: prokaryotic transcriptional regulation (pg 108-111, 115-116, 248-249) After cell differentiates, will stay diff"d and all progeny will be same type. Some highly specialized cells (skeletal muscle cells + neurons) never divide after differentiated. = have to remember + pass on patterns of gene expression. Master cell-type transcription regulator activates transcription of own gene and transcription of other cell-type-specific genes. Every time cell divides, regulator distributed to both daughter cells. Transcription circuits allow the cell to carry out logic operations. Can combine gene regulatory switches to make control devices. Every step in gene expression can be controlled. Genes can be regulated by multiple mechanisms. So far ave looked controls on initiation of gene transcription. Affect how much of gene product is made. Affect amino acid sequence in protein product. Operate after rna polymerase binds to gene"s promoter and begins rna. Transcription attenuation causes the premature termination of some rna molecules.
