BIO207H5 Chapter Notes -Apoptosis, Telomere, Non-Coding Rna

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28 Apr 2012
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If transformed cells stay together in a single mass, the tumor is said to benign. And are replaced with younger cells produced by division of unspecialized. Occasionaly, dividing and differentiating cells derivate from their normal and genetic program and give rise to tissue masses called tumors or neoplasms, The process by which a cell loses its ability to remain constrained in its growth properties is called transformation. This phenomenon is brought about by contact inhibition, a process whereby cells in contact communicate with one another and cell division is stopped. Contact inhibition is reflective of the regulated nature of cell division shown by normal cells. By contrast, transformed cells do now show contact inhibition, instead continuing to grow and divide after contacting neighbors and piling up in multiple layers. If the cells of a tumor can invade and disrupt surrounding tissues, tumor is said to be malignant and is identified as cancer.

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