BIO 1140 Chapter Notes - Chapter 13: Radiography, Cytosine, Metabolic Pathway
12 Aug 2016
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Proteins are encoded by genes made of dna . A genes specify either protein or rna products. Two pieces of research illustrated the connection between genes and metabolism . Alkaptonuria: a human disease that does little harm but is easily detected by the fact that the patient"s urine turns black when exposed to oxygen. Normal people are able to metabolize homogentisic acid, but those with alkaptonuria can"t. This work was the first to show a specific relationship between genes and metabolism. Neurospora: an orange bread mould that is a haploid fungus with simple nutritional needs. Consisting of inorganic salts, sucrose, and a vitamin. The fungus uses only simple chemicals to synthesize all of the complex molecules such as amino acids and nucleotides. Exposed wild-type neurospora to x-rays to cause mutations . Mutant strains that were unable to grow on minimal mediums = nutritional mutants.
