BIO 1140 Chapter Notes - Chapter 3: Cell Plate, Plasmodesma, Connexin

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Functions: provide structure and support, intracellular transport, position organelles within the cell, generate force for cell movement, contribute to cell division. Microtubules globular subunits are tubulin dimers (alpha and beta tubulin tightly bound together w noncovalent bond. Gtp binding site location depend polarity to microtubule: (cid:858)+ e(cid:374)d(cid:859) a(cid:374)d (cid:858)- e(cid:374)d(cid:859) (cid:894)(cid:271)eta down and alpha up) Originate from a central point the mtoc at the centrosome (near nucleus) at the end. Tubulin heterodimers assemble as a single row (protofilament) and stack to form sheets: their 3d structure assembly of 13 protofilaments (alternating btwn alpha and beta tubulin; every. 28 degrees) explains the stiff tube shape with hollow center. Longitudinal (strong bond a with b) and lateral bonds (weak bonds btwn monomers of same type: a-a, b-b) During cell division it if found in star-like arrangement from an interphase cell and can rearrange quickly to make bipolar mitotic spindle.

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