PSYC 3330 Chapter Notes - Chapter assigned: Episodic Memory, Retrospective Memory, Gliosis

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Many disorders can lead to amnesic syndromes in humans, including prominent deicits in episodic memory. Most common clinical amnesic syndrome: involves more than pure memory loss (visuospaial and language deicits) Anatomy involves mtl very early in the course of the disease, as well as lateral temporoparietal and medial parietal cortex: level of dysfuncion in these areas relates to the paient"s memory impairment. Memory deicit is classically conceptualized as a dysfuncion of consolidaion or storage: includes intrusions from interference and discriminability deicits for recogniion. Familiarity tends to be preserved but not recollecion: more recent studies suggest both are impaired. A more liberal response bias, leads to an increase in false memories. Great impairments to prospecive memory: possibly even more than that of retrospecive memory. Involves neuronal loss and gliosis of the hippocampal formaion. Focal lesions of hippocampal subregions and other porions of mtl can be produced by hypoxic- ischemic injury , infecious processes, inlammatory processes and other disorders.

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