HK 2810 Chapter Notes - Chapter 1: Insulin, Electrochemical Gradient, Fluid Compartments

• School: University of Guelph
• Department: Human Kinetics
• Course: HK 2810
• Professor: Laelie Snook

Document Summary

Ingestion by the cell - endocytosis: most fluids pass through the cell by diffusion and active transport, diffusion: simple movement through the membrane caused by the random motion of the molecules of the substance. Phagocytosis: involves large particles instead of molecules, tissue macrophage and some wbcs, initiated when a particle such as bacterium binds with receptors on the surface of a phagocyte, step 1. Cell membrane receptors attach to ligands of the particle: step 2. Edges of membrane envaginate around the entire particle then more and more receptors attach to the the particle ligands - occurring in a zipper like manner: step 3. Actin + other contractile fibrils surround the phagocytic vesicle and contract around its outer edge pushing the vesicle in: step 4. Contractile proteins then pinch the stem of the vesicle to separate it from the cell membrane leaving the vesicle in the cell. Lysosome - dissolves bacterial cell membrane: 2.