PAT 20A/B Chapter Notes - Chapter N/A: Salmeterol, Volume Expander, Terbutaline
28 Feb 2016
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(2)pat20 winter week 12 drug classifications (shock: adrenergic. Adrenoreceptor: beta 2-adrenergic agonists *respiratory agent* (anti- bronchial beta 2. Beta 2-adrenergic agonist drugs: salmeterol (serevent discus), epinephrine (epipen), terbutaline (brethaire) Action: agonist activity at beta 2-adrenergic receptors in bronchial smooth muscle produces bronchodilation. Use: treats/manages obstructive respiratory disease as sole agent or in combination with other bronchodilators/anti-asthmatic drugs. Gi: nausea, vomiting, diarrhea, dry mouth, gastric distress. Concurrent use of nsaids, including aspirin and other ulcerogenic drugs, increased risk of gastric irritation. Calcium, aluminum, magnesium, and iron products decrease absorption. Transient decrease in serum phosphate and calcium levels. Coffee, milk, orange juice, mineral water and other foods increase absorption. Powder for oral inhalation = 50 mcg/blister, in combination with fluticasone. Assess: history of catecholamine hypersensitivity, adequate renal function, lung sounds, diabetes. Lab test evaluation: abgs, fbs (patients with diabetes): crystalloids (low-molecular-weight) *cardiovascular agent* (anti- hypo-colloidal) Crystalloid drugs (low-molecular-weight): 0. 9% sodium chloride (normal saline), 5% dextrose (dextran 40)
