PAT 20A/B Chapter Notes - Chapter N/A: Benzodiazepine, Nonsteroidal Anti-Inflammatory Drug, Theophylline

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(2)pat20 fall week 11 drug classifications (asthma: bronchodilators, anticholinergics *respiratory agent* (anti- bronchial acetylcholine) Anticholinergic drugs: ipratropium (atrovent), tiotropium (spiriva), aclidinium (tudorza pressair) Action: bronchodilation due to local site-specific anticholinergic antagonism of muscarinic receptors in bronchial smooth muscle. Use: maintenance of reversible symptoms associated with copd, treats rhinorrhea associated with common cold and allergic and non-allergic perennial rhinitis. Resp: paradoxical bronchospasm, cough, increase in symptoms, bronchitis and. Others: blurred vision (aerosol), chest and back pain (solution) Hypersensitivity to drug, atropine, soya lecithin, soybean, peanuts. No significant reactions reported, especially with other bronchodilators and steroids. Aerosol = 18 mcg/spray; inhalation solution = 0. 02 %; nasal spray = 0. 03 % (21 mcg/spray), 0. 06 % (42 mcg/spray) Assess: history of hypersensitivity, respiratory function, patency of nasal passage. Dietary management: increase fluid (8-10 glasses/days): beta 2-adrenergic agonists *respiratory agent* (anti- bronchial beta2- adrenoreceptor) Beta 2-adrenergic agonist drugs: salmeterol (serevent discus), epinephrine (epipen), terbutaline (brethaire)

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