BLG 10A/B Chapter Notes - Chapter 26: Angiotensin-Converting Enzyme, Afferent Arterioles, Body Water
14 Apr 2016
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Plasma (pv) = luid portion of blood (~5% of body weight; 20% of ecf) interstitial luid (isf) = luid in spaces between cells. Plasma osmolarity intracellular and extracellular luid osmolarity normally identical (fig 26. 2) o. [na+] is the major determinant of plasma osmolarity. Plasma hyperosmolarity shifts water out of cells. Water input: drinking liquids: eating solid foods, metabolically produced water. Water output: kidneys = major route for elimination of water from body: other water loss from skin, lungs in sweat, in feces. Water excretion: regulation by kidney overview kidneys keep normal efective circulating volume constant regulate plasma luid volume o. Water intake or water losses = blood volume blood pressure kidneys conserve water concentrated (hyperosmotic) low volume urine output (0. 5 l/day; 1200 mosm/l) o. Water intake = blood volume blood pressure kidneys eliminate water dilute (hypoosmotic) high volume urine output (18 l/day; 50 mosm/l) can be regulated dependent upon or independent of plasma sodium concentration.
