BLG 10A/B Lecture Notes - Lecture 26: Plasma Osmolality, Hypovolemia, Synovial Fluid

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Chapter 26 fluids, electrolyte and acid-base balance. Intracellular fluid (icf) compartment: fluid inside cells accounts for 2/3 of total body fluid. Extracellular fluid (ecf) compartment: fluid in two main ecf compartments outside cells accounts for one- third of total body fluid: Interstitial fluid (if): 12 l in spaces between cells. Also considered part of if: lymph, csf, humors of the eye, synovial fluid, serous fluid, and gastrointestinal secretions. Water is the universal solvent solutes are substances dissolved in water. Solutes are classified as nonelectrolytes and electrolytes: nonelectrolytes: most are organic molecules, do not dissociate in water. Examples: inorganic salts, all acids and bases, some proteins. Ions conduct electrical current: greater ability to cause fluid shifts due to ability to dissociate into two or more ions, nacl na+ + cl- (electrolyte; 2 particles) Ecf: major cation: na+ and major anion: cl . Icf: major cation: k+ and major anion hpo42 .

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