NURS 2004 Chapter Notes - Chapter 18: Pheochromocytoma, Adrenal Medulla, Arteriole
28 Jan 2017
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Adrenergic antagonists cause direct blockage of adrenergic receptors. Except for one, all produce reversible (competitive) blockade. Can be divided into 2 groups: alpha-adrenergic blocking agents (drugs that produce selective blockade of alpha- adrenergic receptors, beta-adrenergic blocking agents (drugs that produce selective blockade of beta receptors) Most clinically useful responses to alpha adrenergic antagonists result from the blockade of alpha1 receptors on blood vessels. Essential hypertension hypertension can be treated with alpha adrenergic antagonists. Alpha antagonists lower bp by vasodilation by blocking alpha1 receptors on arterioles veins. Bph blockade of alpha1 receptors in the bladders and prostate can help men with benign prostatic hyperplasia (bph). The benefits derive from reduced contraction of smooth muscle in the prostatic capsule and the bladder neck (trigone and sphincter). ***iv adrenergic antagonists are high alert medications because it can cause devastating effects to pt in the event of med error** Raynauds disease a peripheral vascular disorder characterized by vasospasm in the toes and fingers.
