PHGY 209 Chapter Notes - Chapter --: Sprain, Angiogenesis, Pulmonary Circulation

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Transport mechanisms p. 46-51 microscoping observations of cells: eukaryotic cells: human & multicellular animals/plants, contain nuclear membrane surrounding cell nucleus, prokaryotic cells: bacteria and others, lack membranous structures. Intracellular fluid: all fluid inside cell (cytosol + fluid inside all organelles, including nucleus: cytosol is largest intracellular fluid compartment. Membrane junctions: plasma membranes also play role in cellular interactions to form tissues. K+: present in, for example, muscle cells of heart. Velocity of capillary blood flow: branching of tubular structure influence velocity. If go from one large tube to smaller ones, total cross-sectional area small tubes greater but flow slower --maximizes time for exchange in capillaries. Diffusion across capillary wall: substances move between interstitial fluid and plasma through diffusion / vesicle transport / bulk flow, mediated transport also sometimes, like in brain. [c] > capillary plasma: local metabolic rate ultimately establishes transcapillary diffusion gradients. If tissue increases metabolic rate, need more nutrients and eliminate more wastes.

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