BIO 203 Study Guide - Quiz Guide: Resting Potential, Electrochemical Gradient, Cell Membrane
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Question 1 - at a chemical synapse, the release of neurotransmitter occurs in response to a graded depolarization of the synaptic terminal. An action potential propagating down an axon does not invade an the synaptic terminal because the plasma membrane in the synaptic terminal does not contain voltage-gated na+ channels. However, the depolarization in the axon spreads electrotonically into the synaptic terminal as a graded depolarization (i. e. , graded potential). The graded depolarization is sensed by voltage-gated ca++ channels in the plasma membrane of the synaptic terminal which then open allowing ca++ to enter the synaptic terminal down its electrochemical gradient. The resulting elevated [ca++] inside the synaptic terminal triggers exocytosis of synaptic vesicles and the release of neurotransmitter. Question 2 ): - you discover a drug that prevents voltage-gated na+ channel inactivation gates from opening when they are closed but has no effect on inactivation gates when they are open.