BIOL 1119 Study Guide - Midterm Guide: Lymphatic Vessel, Antigen-Presenting Cell, Classical Complement Pathway
3 Oct 2017
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Functions of lymphatic system: fluid recovery-fluid continually filters from the blood capillaries into the tissue spaces blood capillaries on average reabsorb about 85% (interference with lymphatic drainage leads to severe edema) Thus, lymphatic endothelial cells have large gaps between them. Primary lymphatic organs: red bone marrow is involved in hemopoiesis (blood formation) and immunity. The spaces between the sinusoids are occupied by islands of hemopoietic cells with macrophages and white/red blood cells in all stages of development. After maturing, blood cells enter the sinus and flow away in the blood stream. The one exception is lymphocytes: thymus fxns in the endocrine, lymphatic, and immune systems (releases hormones which affect how t cells mature) Secondary lymphatic organs (most numberous!: lymph nodes-1. Act as a site of lymphocyte activation-so lymph is already mature. Cleanse the lymph: reticular cells (stationary phagocytic) and macrophages in node sinuses remove about 99% of the impurities in lymph mostly by phagocytosis.
