BCHM 210 Midterm: Transport Molecules
Document Summary
Tetrahydrofolate (thf: carries one carbon units and is involved in the synthesis of several amino acids and other biosynthetic reactions, this reaction is catalyzed by serine transhydroxymethylase, a plp containing enzyme. S-adenyosylmethoionine (sam: this is a major methyl donor, sam is synthesized by an unusual reaction between methionine and atp, the methyl group is activated by the positive charge on s making it easy to transfer to other molecules. Tryptophan, an essential amino acid, is synthezed by microorganisms and plants from erythrose. 4-phosphate and phosphoenol pyruvate in a complex pathway consisting of 13 steps. The last two steps of the pathway are catalyzed by tryptophan synthetase. The intermediate is not released from the complex but rather is channeled directly to the active site of the next enzyme: 1. Subunit: catalyzes the formation of indole and glyceraldehyde 3-p. Subunit: catalyzes tryptophan formation from indole and serine.
