Document Summary

In summary, increased cardiac output during exercise ultimately determines the volume of blood that reaches the muscles of interest, carrying along the oxygen and substrates to the muscles and metabolic wastes away from them. Cardiac output is influenced by stroke volume and heart rate. Stroke volume is influenced by end diastolic volume that represents venous return. Venous return is facilitated by a decrease in tpr (resistance) due to metabolic wastes present in the blood. Heart rate is initially influenced by the withdrawal of the peripheral nervous system that inhibits heart rate and contractility and an increase in sympathetic nervous system activity to increase heart rate and contractility. Increased blood volume, to include rbc and plasma volume. Increased ability to carry oxygen and carbon dioxide (rbc) Increased ability to carry proteins, nutrients, and electrolytes and train longer/harder in warmer environments (plasma) Increased cardiac output and stroke volume, lower heart rate.

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