NSCI 4053 Study Guide - Midterm Guide: Malate Dehydrogenase, Triosephosphate Isomerase, Pyruvate Dehydrogenase
19 Dec 2016
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Generates atp anaerobically and provides fuel for aerobic energy generating paths. Does not require oxygen (this is an anaerobic process) Gluconeogenesis: anabolic (building up) process from pyruvate to glucose. Glycolysis: catabolic (breaking down) process from glucose to pyruvate. The purpose of glycolysis, cac and etc is to convert energy from a non usable form (glucose) into a usable form (atp) Ten step glycolysis process converts 1 glucose into 2 pyruvate. Initial energy investment stage: 2 molecules of atp are converted to adp in glycolysis to get the process startedwe are investing energy to make energythis drives the breakdown of glucose to 2 3c-sugar phosphates. Second stage compensates for the investment by converting 4 adp to atp while producing 2 molecules of pyruvate. Net gain of the process is 2 molecules each of atp, pyruvate and nadh. There is no net change in oxidation state of the substrates as they are converted to the products.
