PCB 2061L Study Guide - Midterm Guide: Peptic Ulcer, Gastritis, Vagus Nerve
Document Summary
Inhibits gastrin secretion and thereby inhibits h+ secretion. After ingestion of a meal, h+ secretion is stimulated. After digestion and stomach being emptied, further h+ secretion decreases the ph of the stomach. This low ph is a negative feedback mechanism inhibiting gastrin secretion. Gastritis is inflammation of mucus layer of stomach by bacteria, virus, or autoimmune. Excess acid secretion* by stimulation of parietal cells or excess gastrin. Fresh blood in vomit is sign for bleeding/hemorrhage in upper gi tract. Brownish color of fecal material shows dried blood. Even during destruction of parietal cell for example 70% destroyed by external factors, 30% of unaffected tissue still secretes acid. Over secretion of gastric acid causes: could be due to over secretion of gastrin, which leads to gastritis or gastric ulcer. Abdominal pain especially in left upper quadrant of abdominal and epigastric line (where the pain is)
