CAS BI 203 Study Guide - Quiz Guide: Oral Rehydration Therapy, Sodium Chloride, Intravenous Therapy
7 Dec 2017
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Introduction: explain the rationale for the mspp recommendations in terms of the transmission mechanism(s) for cholera. Transmission is caused by contaminated water and feces which spreads the cholera: cholera toxin preferentially targets intestinal epithelial cells (as opposed to esophageal cells or stomach cells). Epithelial cells have carbohydrate specific receptors (membrane cells specifically). Part i transmission and cellular signaling: cholera toxin inhibits the gtpase activity of the alpha subunit of the g-protein, diagram the pathway (simplified above) targeted by cholera toxin in detail (including subunits and secondary messengers). During her time in haiti, kathryn was bothered by the nearly week-long recovery time for patients who survived the cholera infection and frequently wished for a faster-acting pharmaceutical to improve patient outcomes. A research wants to treat the cells with a chemical that will stop the secretion. Propose a chemical mechanism that the researcher should try and justify your proposal.
