Biochemistry 2288A- Midterm Exam Guide - Comprehensive Notes for the exam ( 51 pages long!)
5 Oct 2017
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Lecture 17: gene expression, the human genome encodes 21 000 protein encoding genes. In any cell types less than 10 000 are expressed: genes are expressed at different levels, the expression of the correct genes is essential for growth and differentiation. In human brain cells, there is a heavy protein where as there could be very little proteins in human liver, even though they have the same genome: the vise versa is also true. Some genes in human liver are expressed more compared to human brain: most diseases are due to altered expression of one or more genes, by therapeutically manipulating gene expression, we have the potential to prevent or reverse diseases. Rna allows to have a lot of expression from one gene and more/less from another gene: since rna can be degraded, expression of a gene can be stopped quickly.
