Biochemistry 2280A Study Guide - Quiz Guide: Heterochromatin, Base Pair, Genomic Library
11 May 2020
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Document Summary
Each cell maintains info to create whole new organisms. One set of rnas is common to almost all cells. Other rnas are specific for the differentiated cell type. Some rnas are only expressed under specific conditions. Expression at protein level is often even more pronounced for each cell type both in abundance and appearance. Transcription only occurs when the gene product is needed. Recognize small sequences (5-10 nucleotide pairs) in the vicinity of the promoter. Domain which can recognize specific dna sequences. Each transcription regulator interacts with a specific cis-regulatory sequence. Many transcription regulators form homo and hetero-dimers. Dynamic nucleosome structure promotes cooperative binding of t. Many transcription regulators interact to control transcription initiation. Many cis regulatory sequences are distal to the promoter. Dna looping is necessary to allow transcription regulators to interact with each other and with rna polymerase. Activators recruit co-regulators which remodel chromatin to open the chromatin.
