BIO315H5 Study Guide - Midterm Guide: Desmosome, Phospholipid, Carbohydrate
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Document Summary
The human cell membrane: all cells are surrounded by a cell membrane, aka plasma membrane, biomembrane, double layer of lipids in which proteins are located, functions: Junctional adhesion complexes: evolution of higher organisms required that single cells form multicellular associations--> began with cell adhesion molecules (cams, homotypic cell adhesion = adhesion of. 2 identical molecules: heterotypic cell adhesion = adhesion of. Em & microinjection studies: connexin proteins spontaneously form connexons, experiment, pure liposomes placed in fluorescent dye lucifer yellow, when purified gap junction protein cx43 was added, dye entered liposomes--> therefore, the spontaneously formed connexons, phosphorylation of cx43 by. Functions adhesion is essential for tissue & organ formation: cell adhesion molecules stick cells together & mediate intercellular communication for proper tissue & organ functioning changes in adhesivity are linked to disease. Ig superfamily members & cadherins are involved in homophilic interactions.
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