BIO 3305 Study Guide - Electrical Synapse, Axon Terminal, Membrane Potential
Document Summary
Neuron-neuron interactions, neuron-endocrine, neuron-muscle: effector neuron + skeletal muscle cell. For diff see slide 6 of lecture 5. Neuron-neuron synapses aren"t always only an axon terminal and a cell body. It can form at various places along the cell (dendrites, cell body, axon, etc. Reach post synaptic membrane specific for the neutrotrans. Resting membrane potential at -70mv and e(ca2+) (nernst eq) is 130mv, both favoring. Calcium entry acts as a trigger in the vesicles. This is the active zone (high conc of all these vesicles waiting for a go-ahead signal (the ca2+) For high efficience, in a sustained matter, presyn cells have 2 mechanisms: reserved amount of vesicles, predocked vesicles waiting on the membrane but not fusing for exocytosis, but vesicle is already there and filled. As soon as the ca2+ arrives, it releases neurotransmitter by exocytosis so you get a quick response, and then the backup reserve can do it"s thing.
