BIO 3303 Study Guide - Final Guide: Retina Horizontal Cell, Electrochemical Gradient, Cell Membrane
21 Apr 2016
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This can happen by suppressing the cell cascade when the drug binds, or lower the number of receptors present on the cells. However, when irregular drinkers consume caffeine, they will experience the full effect of the drug because cells will not have any suppression or have many caffeine receptors present: the effect depends on the receptor. This case is likely a gpcr where one exhibits an excitatory effect and the other exhibits an inhibitory effect: advantages are in the amplification. The greater number of steps, the more potential for a step to amplify a response to the next step (1 pka phosphorylating 10 proteins to activate them). Also, more steps allow for a tighter regulation where each individual step may be regulated independently: when ach binds, it will act as if it were e, which will stimulate an increase in camp levels.
