BIO 2133 Study Guide - Final Guide: Oncogene, Cytosine, Histone Methylation

• School: University of Ottawa
• Department: Biology
• Course: BIO 2133
• Professor: Colin Montpetit

Document Summary

Module 5 - linked genes, extranuclear inheritance, and epigenetics. Can occur because an enzyme/protein needed earlier in the pathway is non-functional in the homozygous recessive condition. The prevents the rest of the pathway from occurring, and the effect of genes later on in the pathway will be masked. Allows us to determine how many genes are involved in a pathway. Only works well with recessive mutations, not dominant mutations. Take two individuals exhibiting the same mutation and cross them. Complementation: the offspring shows a different phenotype than the parents: occurs when the mutation is on different genes, ex. Non-complementation: the offspring shows the same phenotype as the parents: the mutation is on the same gene. Organelle heredity involves dna in chloroplasts and mitochondria. Organelle heredity: inheritance patterns arising from chloroplast and mitochondrial function. Heteroplasmy: variation in the genetic content of organelles. Due to the large number of organelles per cell, not every organelle will necessarily contain the mutation.