BIO 1130 Study Guide - Quiz Guide: Cytokinesis, Metaphase, Prometaphase

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BIO 1130 Full Course Notes

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The prevent this, germ cells are set aside early in the development of the organism and these cells undergo a special sequence of two cell divisions that split the duplicated homologous chromosomes then split the duplicated dna the process is called meiosis. During interphase, the long strands of dna that make up each of the chromosomes are unwound, and regions required for transcription are then available to the cellular machinery that will ultimately take dna sequences and produce the corresponding sequences. However there are two of each chromosome one from mother and the other from father, the maternal and paternal chromosomes. The two sets of paired sister chromatids are the homologous chromosomes sisters are identical to each other and attached by a centromere, but a pair of chromosomal homologs refers to the two different chromosomes, not the duplicated sisters. Together, the homologs and sister chromatids are referred to as a tetrad.

Related Questions

1- Most of a cell's life is spend in this phase of the cell cycle:

--------------------

2- The cell cycle is a highly regulated process.

True

False

3- Cells replicate their DNA during ________________ phase.

4- In animal cells, ________________________ is the indentation of the cell's surface that marks cytokinesis, the final splitting of the membrane, in the process of cell division.

cleavage furrow

binary fission

cell plate

sister chromatids

5- Somatic ("body") cells are _______________ (2n). This means there are two copies of each chromosome.

6- During the _______ phase(s) cells perform their everyday functions.

7- When chromosomes are duplicated the two strands are called _______________________________ and they are linked together at a point called the ____________________.

sister strands; kinetochore

sister chromatids; centromere

dual chromatids; centromere

genes; chromatid

8- New somatic âbodyâ cells are formed by this process:

meiosis

binary fission

replication

mitosis

9- The cytoplasmic division of a cell at the end of mitosis or meiosis, bringing about the separation into two daughter cells.

10- Cells replicate their DNA during ________________ phase.

pucecat917

1.If scientists could increase telomerase production in specific cells, the primary reason for this would most likely be the stopping of

A. meiosis.

B. aerobic respiration.

C. cancer cell formation.

D. All of the answer choices are correct.

E. aging of cells.

2. When DNA replicates

A. the original DNA unwinds, and multiple copies of a region are transcribed before the DNA closes back up.

B. transcription factors determine where to begin DNA replication.

C. None of the answer choices are correct.

D.one strand of the original DNA ends up in each of the new DNA molecules.

E. the original DNA is not affected and a new double-stranded DNA is made from two new strands of DNA.

3. In the biology lab, you observe three different animal cells under a microscope. In one cell, the nucleus is uniformly filled, with no distinct chromosome structure visible. In another, you see the nucleus with two nucleolus areas of more compact chromatin. A third cell is in mitosis, and distinct chromosome strands are visible. The value in packaging DNA in tighter forms of chromatin is for

A. mobility and protection of the DNA molecule during mitosis.

B. prevention of ligase enzyme action during replication.

C. Both answers regarding DNA mobility, protection and regulation in mitosis and transcription are correct.

D. regulation and protection of the DNA during transcription.

E.insuring that sister chromatids will be attached prior to replication.

In addition to identifying the genetic material, the experiments of Avery, MacLeod, and McCarty with different strains of Streptococcus pneumoniae demonstrated that

	DNA is a double helix.
	DNA may be taken up by bacterial cells and be active.
	DNA is present in bacteriophage T2.
	eukaryotic cells may be genetically transformed.
	DNA binds to the cell wall of the bacterium.

In order to show that DNA in cell extracts is responsible for genetic transformation in Streptococcus pneumoniae, important corroborating evidence should indicate that _______ also destroy transforming activity.

	temperatures high enough to kill cells
	enzymes that hydrolyze proteins
	enzymes that hydrolyze DNA
	enzymes that hydrolyze polysaccharides
	enzymes that hydrolyze RNA

Based on what you have learned about the experiments conducted by Griffith and Avery and colleagues with bacteria, which of the following would result in transformation of living R cells?

	Pure RNA from S cells
	Cell-membrane extracts from S cells
	A mixture of pure RNA and protein from S cells
	Cell-free extracts from S cells
	Pure protein from S cells

A-T base pairs in a DNA double helix

	form three hydrogen bonds with each other.
	are more heat-stable than G-C base pairs.
	are of a substantially different length than G-C base pairs.
	are not accessible to DNA binding proteins.
	are chemically distinct from G-C base pairs.

If 23 percent of the bases in a sample of double-stranded DNA are adenine, what percentage of the bases are uracil?

	27
	50
	0
	73
	23

The uniform diameter of the DNA structure provides evidence for

	antiparallel DNA strands.
	a right-handed helix.
	a double-stranded helix.
	3â² end phosphorylation.
	purineâpyrimidine pairing.

If a sequence of one strand of DNA is 5â²-TGACTATC-3â², what is the complementary strand?

	5â²-ACTGATAG-3â²
	3â²-TGACTATC-5â²
	3â²-ACTGATAG-5â²
	3â²-ACTGATAG-3â²
	5â²-TGACTATC-3â²

What structural aspect of the DNA facilitates dissociation of the two DNA strands for replication?

	3â² end phosphorylation
	Purineâpyrimidine pairing
	Antiparallel DNA strands
	Covalent bonds between sugars and phosphate groups
	Hydrogen bonding between paired bases

If the MeselsonâStahl density gradient experiment had resulted in two bands of DNA molecules after only one round of replication, one containing only ¹⁵N and the second only ¹⁴N, this result would have indicated that replication was

	unidirectional.
	dispersive.
	conservative.
	bidirectional.
	semiconservative.

10.

The nucleoside analogue acyclovir, which is used to treat herpes simplex virus (HSV) infections, lacks a 3â² hydroxyl group (âOH). Predict what will happen if the host cell DNA polymerase incorporates a molecule of acyclovir into an elongating strand of HSV DNA.

	The replication complex will no longer bind to origins of replication.
	The DNA polymerase will only incorporate acyclovir molecules.
	Acyclovir will bind single-strand binding proteins.
	DNA polymerase will not be able to link a successive nucleotide.
	Acyclovir will block the activity of the DNA helicase.

11.

Which of the following does not demonstrate the stability of the DNA double helix?

	Single-strand binding proteins are required to keep the strands apart.
	Paired bases form hydrogen bonds.
	High temperatures are required to denature it.
	DNA synthesis requires energy.
	DNA helicases require ATP.

12.

What effect would a primase inhibitor have on DNA replication?

	DNA polymerase would not be able to add bases to the DNA.
	Primase would be blocked from joining the DNA replication complex.
	Primase would not be able to provide primers for DNA polymerases.
	DNA polymerase would not be able to use DNA as a template.
	There would be no effect on DNA replication.

13.

To replicate their DNA in a timely manner, most eukaryotic chromosomes

	normally have uncoiled DNA.
	have multiple origins of replication.
	contain linear molecules of single-stranded DNA.
	have two replication forks that move in the same direction.
	are composed entirely of DNA.

14.

Which statement about DNA replication is false?

	Okazaki fragments are synthesized as parts of the leading strand.
	Error rates for DNA replication are reduced by proofreading of the DNA polymerase.
	The sliding clamp increases the rate of DNA synthesis.
	Replication forks represent areas of active DNA synthesis on the chromosomes.
	Ligases and polymerases function in the vicinity of replication forks.

15.

In many eukaryotes, there are repetitive sequences called telomeres at the ends of chromosomes. After successive rounds of DNA replication, the _______ strand becomes shorter. In some cells, an enzyme called _______ repairs the shortened strand.

	leading; telomerase
	lagging; telomerase
	lagging; DNA polymerase I
	leading; DNA polymerase I
	leading; replicase

16.

A researcher studies normal human fibroblast cells. They can be maintained in culture but die off after about 30 cell generations. Unexpectedly, a colony of cells continues to survive and divide past 30 generations. Which scenario is most likely true for these cells?

	DNA polymerase is constantly active.
	Primase is able to extend the telomeres.
	The mismatch repair system is extra efficient.
	The telomerase gene is being expressed.
	The cells do not need the ends of their chromosomes.

17.

If DNA polymerase III introduces an incorrect nucleotide, what is the first corrective action made by the DNA repair system?

	The replication complex excises the incorrect nucleotide.
	The excision repair proteins remove the incorrect nucleotide.
	The mismatch repair system scans for base-pairing mismatches.
	There is no correction, because nucleotide errors by DNA polymerases are not repaired.
	DNA ligase connects the correct nucleotide.

18.

Choose the correct order of the following four events in the excision repair of DNA:
(1) Base-paired DNA is made complementary to the template.
(2) Damaged bases are recognized.
(3) DNA ligase seals the new strand to existing DNA.
(4) Part of a single strand is excised.

	1, 2, 3, 4
	2, 1, 3, 4
	3, 4, 2, 1
	2, 4, 1, 3
	4, 2, 3, 1

19.

Six complete cycles of PCR should result in a _______-fold increase in the amount of DNA.

	64
	32
	12
	128
	6

20.

When double-stranded DNA is heated to temperatures above 90Â°C, it denatures. Denaturation is a process that

	breaks covalent bonds.
	hydrolyzes DNA.
	separates double-stranded DNA into two single strands.
	causes new hydrogen bonds to form.
	irreversibly destroys the double helical structure.

BIO 1130 Study Guide - Quiz Guide: Cytokinesis, Metaphase, Prometaphase

BIO 1130 Full Course Notes

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