MBG 2040 Study Guide - Final Guide: Robert Lehman, Telomerase Rna Component, Dnaa

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The standard b-form dna helix of watson and crick. Basic features of dna replication in vivo (cid:498)it has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material(cid:499) The watson-crick double helical dna model predicted replication by a semi- conservative mechanism. But, there were other possibilities through an experiment, meselsohn and stahl proved that the semi- conservative model was the correct copying mechanism for dna. Conservative model: original dna (parent) stays intact and then another completely new copy is made (original dna= conserved) (both strands go to one molecule) Dispersion model: when double helix replicates, each strand of daughter dna contains both new and old chunks (old dna is dispersed everywhere) Second replication overview conservative model: each parent stays intact, so you get one 15/15 and three 14/15s semi conservative, each parent is half conserved, so you get two 14/15s and two 14/14s.

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