MBG 2040 Lecture 1: MBG 2040 Ch. 10

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The discovery of reverse transcriptase in retroviruses and retro- like viruses (howard temin and. Standard b-form dna helix of watson and crick: It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material. Basic features of dna replication: general features, replication occurs semiconservatively, usually proceeds bidirectionally from each origin of replication. Dna replication is semiconservative: each dna strand serves as a template, complementary base pairing determines sequence of new strand, each strand of parental helix is conserved. 15n will have a greater density than the dna of cells grown on medium containing 14n. Densit y of dna is similar t o cscl! When cent r if uged an equilibr ium densit y gr adient is f or med! Dna will move t o a posit ion wher e it s densit y is equal t o t he.

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