PAT 20A/B Study Guide - Midterm Guide: Enteric Coating, Oral Mucosa, Dosage Form

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Document Summary

Many types immediate release, enteric coated, extended release, etc. Sublingual: absorbed rapidly through highly vascularized tissue under tongue. Does not go through liver ( does not undergo first pass effect) Buccal: same as sublingual but through oral mucosa between cheek and gum. Absorbed directly into bloodstream and delivered rapidly to their site of action: rectal administration, anything through the gi tract, barriers to absorption: Capillary wall most drugs pass freely: absorption patterns. For most meds this is the fastest route: parenteral: any route of administration other than the gi tract. Usually injection by any method: chemicals may penetrate the skin and get into the circulation, example: No significant barriers to absorption drug passes through capillary wall. Absorption pattern determined by: drug solubility in water, and blood flow. Subcutaneous injections: parenteral injections into the fatty subcutaneous tissues under the dermal layer of the skin. Absorption through these injections can be increased by applying heat to or by massaging the injection site.