BIOL 330 Final: Bio 330 exam notes

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White blood cells use this to kill virally infected cells. Fas ligand on surface of lymphocytes or natural killer cells. At the membrane of the infected cell- building a complex through protein-protein interactions. Protein modified by cleavage in the cytosol of the responding cell tbid inhibits bcl2. Microtubule dynamics assembled tubulin hydrolyzes gtp starts from negative end and grows towards the positive end tubulin assembles dynamically unstable and polarized microtubules. Maps mediate the assembly, dynamics and function of microtubules. All microtubules are nucleated from microtubule-organizing centers (mtocs) and many remain anchored by their negative ends. Centrosome mtocs consist of 2 centrioles and the surrounding pericentriolar material. Form rigid gels, networks and linear bundles. Regulated assembly from a large number of locations. Contractile machinery and network at the cell cortex. Regulated assembly from a small number of locations. Microtubules are found in many different locations, and have all similar structure.

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