NUR5111 Study Guide - Final Guide: Attention Deficit Hyperactivity Disorder, Indometacin, Adrenergic Agonist
3 Mar 2021
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Stimulates opioid receptors to alter pain perception & emotional responses. Pethidine inappropriate for use in elderly due to toxicity. Produce less than maximal effects at the receptor. Prolonged onset of action, not suitable for acute pain. Precipitate withdrawal symptoms in people physically dependent on opioids. Naloxone: short-acting & administered parenterally; used mainly for treatment of overdoes or for reversal of opioid depressant effects. Overdose may lead to toxicity & suppression of the respiratory centre in the medulla. Patients with liver damage may accumulate the active drug & are very sensitive to the depressant effects. Renal disease can extend the half-lives of opioids & cause respiratory depression. Generally less effective analgesics with lower dependency potential & less severe withdrawal symptoms. Use as analgesics not recommended as they may precipitate pain or withdrawal reactions in patients taking other opioids. Used to reverse adverse/toxic effects, overdoses or dependence of opioid agonists such as morphine & heroin. Can treat respiratory difficulties caused by opioids.
