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OC4670932Lv1
16 Feb 2023
Exploring the potential impacts of individual factors on ADME
Scenario:
Joanne is a 35-year-old female with a medical history of stomach complaints but no evidence of ulcer. When Joanne visited the clinic this morning, she weighed in at 324 pounds. ¡ She presented with upper respiratory symptoms attributable to allergy and was prescribed a decongestant and an antihistamine.
- Read the scenario a couple of times, making sure to pay attention to the details.
- Write down factors about the individual that you can identify from the scenario.
§ Think about the factors discussed on slides 4 and 5
- Look at the factors that you listed in Step 2 and write out the ones that you
believe should be considered when determining the drug dose that should be
given.
§ Are there any factors that you believe would require the drug dose to be
increased or decreased?
- For each factor you identified in Step 3, write down what part of ADME they could
affect.
§ In some instances, it could be more than one.
§ You can also consider administration here.
- Pick one of the factors you identified in Step 4 and one of the parts of ADME (if
there is more than one) and explain in detail how that factor affects that part of
ADME.
- Make a recommendation, based on the explanation that you provided in Step 5,
for how the drug dose or other feature should be changed.
- Repeat steps 5 and 6 for each of the other factors you identified, each time
focusing on a different part of ADME (or another feature).
Exploring the potential impacts of individual factors on ADME
Scenario:
Joanne is a 35-year-old female with a medical history of stomach complaints but no evidence of ulcer. When Joanne visited the clinic this morning, she weighed in at 324 pounds. ¡ She presented with upper respiratory symptoms attributable to allergy and was prescribed a decongestant and an antihistamine.
- Read the scenario a couple of times, making sure to pay attention to the details.
- Write down factors about the individual that you can identify from the scenario.
§ Think about the factors discussed on slides 4 and 5 - Look at the factors that you listed in Step 2 and write out the ones that you
believe should be considered when determining the drug dose that should be
given.
§ Are there any factors that you believe would require the drug dose to be
increased or decreased? - For each factor you identified in Step 3, write down what part of ADME they could
affect.
§ In some instances, it could be more than one.
§ You can also consider administration here. - Pick one of the factors you identified in Step 4 and one of the parts of ADME (if
there is more than one) and explain in detail how that factor affects that part of
ADME. - Make a recommendation, based on the explanation that you provided in Step 5,
for how the drug dose or other feature should be changed. - Repeat steps 5 and 6 for each of the other factors you identified, each time
focusing on a different part of ADME (or another feature).
sharmaad2003Lv10
17 Feb 2023
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17 Feb 2023
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rishirost12Lv5
17 Feb 2023
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17 Feb 2023
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1speedypedroLv4
17 Feb 2023
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16 Feb 2023
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davidsnape2Lv8
16 Feb 2023
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