janincarmela

25  You get 20 observations (20 X and 20 Y) and run a regression, and then you conduct a test: . You have calculated the t statistic that equals to 2.01. What can you say about the p-value of the test?

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Consider the regression model . Which of the following statement about the 95% confidence interval of is true?

The table below shows a random sample data from a linear PRF that satisfies the CLRM assumptions. In particular, assume that the population variance of the error term is 16.

Calculate .

Imagine that you are a geneticist at a hospital and you are given a file for a patient
whose family has a history of cancer.
The patient, John Doe, is 18 years old and has had a biopsy done on a tumorous
growth in his adrenal gland. He has a sister, Jane, and a brother, Bob, who are younger
than he is and who are both healthy. His mother, Betty, has a diagnosis of breast
cancer. John’s father, Joe, and John’s paternal grandparents have no history of cancer.

Betty is one of four children. Her brother, Tom, and sister, Lucy, have never had cancer
or signs of cancer. Both Tom and Lucy are older than Betty. Betty had another brother,
Jake, who died very young of leukaemia. Tom has monozygotic twin daughters who are
healthy. Betty’s father, Don, died of soft tissue sarcoma in his thirties. Betty’s mother is
alive and healthy. Betty’s paternal grandmother, Don’s mother, died of a brain tumor in
her thirties. Don had no siblings.

As part of your research, you also consult the OMIM (Online Mendelian Inheritance in
Man) database and come up with a short list of candidate genes could mutate to
cause John’s tumor.

MULTIPLE ENDOCRINE NEOPLASIA, TYPE I; MEN1
OMIM #13110
• Associated with tumors of the endocrine (hormone producing) glands. Originally known as Wermer syndrome.
• Most common tumors involve parathyroid gland, islet cells of the pancreas, and pituitary gland.
• Other endocrine tumors include adrenal cortical tumors, carcinoid tumors and rare pheochromocytomas, as well as tumors in other parts of the digestive tract.

LYNCH SYNDROME I
OMIM #120435
• Also known as hereditary non-polyposis colorectal cancer (HNPCC).
• Significantly increased risk of developing colorectal cancer.
• Increased risk of developing other types of cancers, such as endometrial (uterine), stomach, breast, ovarian, small bowel (intestinal), pancreatic, prostate, urinary tract, liver, kidney, and bile duct cancers.

LI-FRAUMENI SYNDROME; LFS
OMIM #151623
• Most common types of cancer osteosarcoma (bone cancer), soft-tissue sarcoma, acute leukemia, breast cancer, brain cancer, and adrenal cortical tumors, which is an organ on the top of the kidney.
• Increased risk for melanoma, Wilms' tumor, and cancers of the stomach, colon, pancreas, esophagus, lung, and gonadal germ cells (sex organs) have also been reported.

CARNEY COMPLEX, TYPE 1; CNC1
OMIM #160980
• Associated with spotty skin pigmentation; myxomas, which are benign (noncancerous) connective tissue tumors. Tumors can be benign or cancerous.
• Symptoms develop when a person is in his or her early 20s.
• Other common features are Cushing’s syndrome and multiple thyroid nodules (tumors). Features a combination of weight gain, high blood pressure, diabetes, and easy bruising, caused by the overproduction of the hormone cortisol.

NEUROBLASTOMA, SUSCEPTIBILITY TO
OMIM #256700
• Solid cancerous tumor that begins in the nerve cells outside the brain of infants and young children. It can start in the nerve tissue near the spine in the neck, chest, abdomen, or pelvis, but it most often begins in the adrenal glands.
• Develops most often in infants and children younger than 5.

VON HIPPEL-LINDAU SYNDROME; VHL
OMIM #193300
• Associated with tumors arising in multiple organs. Include hemangioblastomas, spinal cord, and eye.
• Increased risk of developing clear cell renal cell carcinoma, pheochromocytoma, and pancreatic neuroendocrine tumor.
• Other features - kidney cysts, pancreatic cysts, epididymal cystadenomas, and endolymphatic sac tumors.

1. (3) To confirm that John has a mutation in the suspected gene(s), what molecular
technique will you use? What tissue would you use for this test and why?

2. (3) If it turns out that there is a mutation in the suspected gene(s), how can you
experimentally determine that the mutation is located in protein-coding region of the
gene(s)?

use java Use a GUI to open the file and display words create another class called WordGUI that will be a complete JFrame with a menu bar and menus. There should be two menus: one called File and another called List. The File menu should have the menu items Open and Quit. The List menu should have five menu items: A, E, I, O, and U.The content pane of the GUI should have a grid layout of one row and two columns. Clicking on File >Open should allow the user to choose a file. That file should be displayed in the left column, with the lines numbered (starting at 1). When the user clicks on List a choice can be made of one of the five vowels. Clicking on a vowel should list all the words starting with that vowel in sorted order in the right column. Each word should have the line number on which it appeared. Create a class to record the word and its line number create a class called WordLine that will have two instance variables: a String for the word, and an int for the line number on which the word appears. There should be a two-argument constructor, and error checking with an exception thrown if the line number is less than 1. You may store the WordLineobjects in either an array or a linked list. The exception thrown should be an InvalidWordLineException which you can create by extendingIllegalArgumentException    

A new sensor to detect bloodborne biomarkers is in development. The sensor uses enzymes immobilized on the surface of a flat strip (0.1cm X2cm) of polymer material to collect the biomarkers for increased detection. The enzymes rapidly convert the biomarkers into a secondary product that can be detected more easily. In an experiment, you collect blood from a patient that contains the biomarker and gently flow it over the sensor material at a velocity of 2 cm min". The flow is parallel to the long axis of the strip and the temperature is maintained at 37°C.

If the diffusivity of the biomarker in blood was determined to be 5.87 X 10^6 cm^2/s, what is the mass transfer coefficient for this process?

Your data indicates that 0.023 milligrams of biomarker were collected in 1 hour. Based on this measurement, what is the biomarker concentration in the blood?

1) The term given to the mass of fibrocartilage repair tissue that becomes bone and bridges the gap between fracture fragments is _________. 2) The most common adolescent spine deformity, especially in girls, that involves abnormal rotation as well as medial/ lateral curvature of the spine is called _______.

The most common deformity seen in club foot is ________

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I need the answer for these questions

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I need answer for these questions

The vastus lateralis is almost composed of entirely type I (slow-twitch glycolytic) and type IIA (fast-twitch glycolytic oxidative glycolytic) fibers. In many samples of this muscle no type NB fibers (fast-twitch glycolytic) are found. There are nearly twice as many type I fibers compared to type IIA fibers. In the vastus lateralis, this is reversed (there are more type IIA fibers versus type I fibers).

1. Record the journalentries for all items (#1 - #28) in the GJ (General Journal) forFifth Cousin Media LLC in EXCEL. Use Data-validation toolà List (for the list use chart of accounts) for columnC in GJ. This tool is explained in the instructionalvideo.

2. Post the transactionsshown above in the appropriate general ledger accounts, useT-accounts tab in EXCEL. Post the transactions byreferencing cells in the GJ tab. Do not simply re-type the amounts.Use formulas to calculate balances for all T-accounts.

3. Prepare an AdjustedTrial Balance in EXCEL. Use cell references from T-accounts or theGJ when appropriate; use formulas to total the debits andcredits.

4. Name your fileusing your initials (e.g. ACC3313FCM_Part1_LK.xls) and upload the file to TRACS in the“Assignments” section by 7:30am Tuesday, Sept. 4,2018. PRINT OUT AND BRING hard copies of your GJ entries,t-accounts and Adjusted Trial Balance to class on Tuesday, Sept. 4.The solution will be reviewed in class.

5. A correct AdjustedTrial Balance will be available on TRACS at 9am on September 4. Useit to prepare an Income Statement, a Statement of RetainedEarnings, and an unclassified Balance Sheet in EXCEL. Use formulaeas appropriate.

6. Prepare closing entrieson the separate tab in EXCEL.

7. Prepare a Post-ClosingTrial Balance in EXCEL; use formulae to total the debits andcredits. Name your file using your initials (e.g.ACC3313 FCM_Part2_LK.xls) and upload the file to TRACS inthe “Assignments” by 7:30am Tuesday, September11.

Note: Part of your grade will relate to your use of EXCEL. Youmust use cell references and formulas where possible.

FIFTH COUSINMEDIA CASE (60 points). ACC3313 FALL-18

Fifth Cousin Media (FCM) provides social mediamarketing and consultation services for its clients. The followingtransactions occurred in December 2017. Transactions up to November30 have been correctly recorded unless otherwise specified. OnDecember 1, you took over the controller position and are nowresponsible for recording all transactions and preparing thefinancial statements.

The chart of accounts and trial balance as of November 30,2017 are in ACC3313 FCM Template.xls(TRACS-Resourses-Part1-Accounting Cycle Problem)

1. On February3, 2017, FCM signed an agreement with Deion Sanders to providemedia consulting for his football camp. On December 1, FCMcompleted some of the work for Sanders, and issued an invoice for$15,000. Full payment was received on January 15, 2018. Note: theproject did not involve video production.

2. On December1, to prepare for expansion, FCM issued 1,000 shares of stock for$90 per share and signed a $20,000 note that is due November 20,2022. The note carries a 4.5% annual rate of interest which is tobe paid semi-annually so the first interest payment will be madeMay 31, 2018. (Do not forget to record accrued interest at the endof the year). On December 3, FCM purchased land for $100,000 onwhich to build a 4,000 sq. ft. facility.

3. On November15, 2017, FCM sent an invoice for $170,000 to the LivestrongFoundation for creating a promotional video. On December 2, FCMreceived the $170,000 payment from the Livestrong Foundation

4. On November30, 2017, FCM purchased, received, and recorded $4,000 of suppliesfrom VimBoot on account. On December 4, FCM paid VimBoot for thesupplies purchased the previous month.

5. On November30, 2017, FCM accrued $230 for that month’s AT&T Internet andtelephone bill. That ATT&T bill was paid on December 5.

6. FCM recorded the purchase of a $1,600 insurance policy on May 31,2017, for coverage from June 6 through December 6, 2017. No otherentries related to this insurance policy have been made. FCMpurchased a new 12-month policy on December 6 for $2,920 cash.

7. On December7, NBC Sports contacted FCM about a potential video project. OnDecember 15, FCM paid $1,000 to a consultant to gather focus groupsto determine if there was sufficient demand for the project NBCSports proposed. On December 30, the consultant provided TCM withthe report discussing the results of the focus groups.

8. On December11, FCM purchased two computers from Dell Inc. for $4,900 each. FCMpaid $500 down with a check; the remaining balance is due in 30days (n/30). The computers have an estimated life of three yearsand a salvage value of $100.

9. On December12, an invoice in the amount of $120 was received from FedEx fortransportation-in on the computers purchased on December 11. Theinvoice was paid the same day by check.

10. On December 15, a $55,000 socialmarketing project was completed for JonyJones. The invoice was sentwith a due date of January 25, 2018. FCM failed to recordtransaction.

11. On August 1, 2017, a $12,000contract was signed for a social marketing project with OutrightFitness and FCM received the full payment on that date. On December17, FCM completed the project for Outright Fitness.

12. On December 18, FCM had anunpleasant communication with O-Dij-Games, a company producingon-line video games and a long-time customer of FCM. O-Dij-Gameshad recently difficulties with revenue generation and financing.O-Dij-Games’ management expresses an unwillingness to pay FMC theremaining $1,500 due to FMC because of dissatisfaction with theoutcomes from FCM’s social media campaigns. O-Dij-Games indicatedits intention to never use FMC services in the future. FCM wroteoff the O-Dij-Games’ outstanding balance. FCM uses the allowancemethod for bad debts.

13. On December 19, FCM received$28,000 payment for a promotional project that was completed forChuck Nash Chevy in October 2017. The receivable had been recordedupon completion of the project.

14. On November 22, FCM borrowed$15,000 on a 5%, 30-day note from SocialVid Consulting. On December22, FCM repaid the note and interest.

15. On December 22, FCM issued a $340check to reimburse an employee for travelling to Houston to make apresentation to potential customers.

16. On December 29, supplies of $900were purchased on account (n/30) and delivered.

17. A cash dividend of $9,700 wasdeclared and paid on December 30.

18. Beginning in April 2017, FCMperformed a variety of social media services for Art Unlimited overa period of six months. Art Unlimited failed to make its lastpayment of $11,000, which was due November 15, 2017, because it waswaiting for money to be transferred to it from a related artfoundation. On December 31, FCM allowed Art Unlimited to replaceits account receivable with a six-month note receivable due June30, 2018; the note carries a 5% interest rate.

19. All six FCM employees are monthlypaid. Wages and Salary Expense for December 2017 was $9,180, whichwill be paid on January 2, 2018.

FCM used the followinginformation to make adjusting entries:

20. A physical count of suppliesindicated that, as of December 31, 2017, $800 worth of supplieswere on hand.

21. On December 15, a $55,000 socialmarketing project had been completed for JonyJones, but FCM forgotto record the transaction. You identify this oversight on December31^st.

22. On November 1, YMCA-Austin begannegotiations with FCM for $42,000 of video production services. FCMwould perform the video production services for YMCA-Austin over a12-month period. FCM signed the contract on December 1, 2017 andbegan shooting immediately. Payments for the work are to be spreadevenly throughout the 12-month period, with FCM billing YMCA-Austinon the last day of every month. The check for December’s work forYMCA was not received until January 1^st, 2018.

23. December 2017’s electricity billof $100 was accrued on December 31 but was received and paid onJanuary 2^nd, 2018.

24. December’s Internet and telephonebill of $230 was accrued at month end and paid on January 3,2018.

25. Make the adjusting entry necessaryto record depreciation expense for all of 2017. Your assistant hascalculated depreciation for the year, as shown in in the “ExtraInfo” tab. FCM’s management has decided that a full month ofdepreciation is recorded if an asset is held for 15 days or more;if the asset is used less than 15 days in a month, no depreciationis recognized. For example, the equipment acquired on March 19 isdepreciated as if it had been purchased bought on April 1. Acomputer sold on November 11 is depreciated as if it had only beenused until October 31.

26. A lease payment of $6,000 forrenting the office was made on October 1, 2017, for rental throughSeptember 30, 2018. The asset account was properly adjusted forOctober and November. The cost of leasing the office needs to bemade for December 2017.

27. The Allowance for DoubtfulAccounts should be established at 1% of Accounts Receivable as ofDecember 31, 2017. Compute the balance after making the Decemberadjusting entries.

28. During 2017 there were four notespayable outstanding (the three indicated below and the one repaidon December 22). Interest for two of these notes (SnapCut andWestBestVideo) is paid at maturity; interest on the Wells Fargonote is paid semiannually. Proper accruals of the interest weremade as of November 30, 2017. Interest for December 2017 needs tobe recorded.

Your assistantcalculated interest for December 2017 below:

29. Insurance expense for December2017 needs to be recorded using the number of days in the insurancepolicy.

Part 1 (8 points):

List four procedures that a business should use to control its cashpayments.

Part 2 (9 points):

Determine the due dates and discount amount for the followingexample:

A software company frequently purchases merchandise on account.When it receives an invoice, a clerk puts a processing stamp on theinvoice indicating the due date, the amount of any discount, andthe amount to be paid.

The following invoices were received during March:

Instructions: The first invoice has been completedas an example. Prepare a form similar to the one that follows usingyour spreadsheet software. For each invoice do the following:

1. Determine the due date. Assume thatthe software company always pays invoices within the discountperiod.
2. Calculate the discount amount, ifany.
3. Calculate the amount to bepaid.
4. Calculate the amount the softwarecompany will save by taking advantage of all discounts.

ABC Co. receives invoice for Insurance on quarterly basis (March, June, Sept and December). Quarterly invoice is amounting to Php 3,000.00

How much Insurance expense should be accrued in February?