BIO 280 Chapter Notes - Chapter 1: Innate Immune System, Inflammasome, Lymph Node
Document Summary
I recommend answering the questions at the end of the chapters as an assessment of your knowledge. Hsc: understand the functions (not necessarily the structures) of malt, spleen, and. Innate immunity: be able to answer what components of the immune system are responsible for flu-like symptoms, be able to explain from how cells get recruited into sites of inflammation. Include which molecules upregulate, recruit and activate cells other cell types. Cams, integrins, chemokine receptors: understand how prr work in general and critical aspects of why they exhibit non-specific specificity towards pamps, you need to know the major prr groups: tlr, rlr, nlr, and clr. Be able to identify what type of pathogens they mainly recognize and what type of immune responses each group generates: tlr activate proinflammatory responses either through nf-kb leading to. Know which cells express ccr7 and what does that do for these cells: know what the acute phase response is, what anti-pathogen events it initiates, the main.
