PHRM 100 Study Guide - Midterm Guide: Hyaline Cartilage, Synovial Joint, Rheumatoid Arthritis
Document Summary
Cartilage: hyaline cartilage, fibrocartilage, elastic: hyaline cartilage contains chondrocytes which are mature cartilage, produce pro-collagen and proteoglycans which form intracellular matrix, surrounded by perichondrium (contains blood vessels and nerve fibers) Osteoarthritis: more prevalent in elderly; chronic; thinning of cartilage, inflammation of synovium. Rheumatoid arthritis: young and old; inflammatory disease (constant inflammation in joints) Ligaments: fibrous tissue connecting bone to bone and stabilize joints; provide rotational stability. Tendons: tissue connecting muscle and bones; composed of collagen fibers. Kinesthesis: constant feedback about what the muscles are doing; senses body part location and movement: coordinated by proprioceptors (muscle spindle afferent and mechanoreceptors) Mammalian muscle spindle: stretch receptors that convey changes in muscle length to brain (via afferent nerves) Ia innervates dynamic nuclear bag, static nuclear bag and nuclear chain fibers. Ii innervates static nuclear bag and nuclear chain fibers. Ia and ib= aa fibers: sensitive to vibration, sense limb position and movement.
