Biology And Biomedical Sciences BIOL 2960 Lecture Notes - Lecture 29: Transcription Factor Ii D, Tata-Binding Protein, Atp Hydrolysis
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Clicker: these are true about both eukaryotic and prokaryotic transcription: Both use dna sequences near the transcription start site to position the polymerase for initiation (promoters) Both have to open the dna at the transcription start site. Gene expression changes in single-celled organisms allow the organism to adapt to different environmental conditions. Gene expression changes in multi-cellular eukaryotic organisms allow formation of different cell types as well as adaptation to different environmental conditions. In prokaryotes, it"s not compartmentalized, and transcription and translation happen at the same time essentially. In eukaryotes, there are rna processing events before being transported to the cytoplasm, whereas in prokaryotes there is basically none. Cis-acting elements (dna regulatory sequences that bind proteins) are more varied and can be positioned in different configurations relative to the coding sequence. Extensive processing of primary transcript destined to become mrna in eukaryotes. Activators enhance weak polymerase binding; repressors interfere with polymerase binding.