BIOS 2400 Lecture Notes - Lecture 16: Functional Residual Capacity, Intrapleural Pressure, Bronchiole

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Bios 2400 - chapter 16 - respiratory physiology. Intrapleural pressure: pressure in the intrapleural space, pressure is negative, due to lack of air in the intrapleural space, atmospheric pressure: 760 mm hg, transpulmonary pressure, the difference between intrapulmonary and intrapleural pressure. Intrapulmonary pressure > intrapleural pressure: keeps the lungs against the chest wall, allows lungs to expand during inspiration, during inspiration, atmospheric pressure is > intrapulmonary pressure (-3 mmhg = 757, during expiration, boyle"s law. Intrapulmonary pressure (+3 mmhg = 763) > atmospheric pressure: changes in intrapulmonary pressure occur as a result of changes in lung volume, pressure of gas is inversely proportional to its volume. 34 weeks; could have collapsed lungs; treated by giving surfactant) & ards (occurs in adults due to septic shock; lung compliance and surfactant is decreased; not treatable with giving surfactant) Intrapulmonary pressure changes from 3 to +3 mm hg. Inflammation contributes to increased airway responsiveness to agents that promote bronchial constriction.