Fill in the blanks below, using words from the supplied word bank (case-sensitive). Not all words will be used, and some may be used more than once.
When the naive helper T cells are initially activated on a ________, most differentiate into wither TH1 ot TH2 effector cells, depending mainly on the ________ in their environment. TH1 cells activate ________, ________, ________, while TH2 cells activate mainly ________. In both cases, the effector helper T cells recognize the same complex of foreign peptide and _______ protein on the target cell surface as they initially recognized on the ________ that activated them. They activate their _______ by a combination of membrane-bound and secreted co-stimulatory proteins. One membrane signal protein used by TH1 and TH2 cells is _____ lignad.
dendritic cell nuclei target cells class II MHC
cytotoxic T cells basophils B cells CD40
signal proteins macrophages dendritic cell cancer cells