BIOL 2100 Lecture Notes - Lecture 5: Reaction Rate, Chemical Bond, Trypsin
Document Summary
What is metabolism: chemical reactions, produce energy, use energy to create substances to sustain life. Metabolic pathways: sequences of chemical reactions, enzymatically catalyzed. Enzymes and chemical reactions: catalysts, substrate. Increase chemical reaction rate: not consumed during reaction. Enzymes: energy of activation (ea: energy to break chemical bonds and start reaction, enzymes lower the energy of activation and speed up the reaction rate. Naming enzymes group or chemical bond: usually add the suffix -ase onto the end of the substrate, ex: urease = urea is the substrate, grouped depending on the type of reaction they catalyze, exceptions, lysozyme, pepsin, trypsin. Inorganic: certain metal ions (magnesium, calcium); trace elements (iron, zinc) Of substrate there is steep increase in the rate of reaction. All of the active sites of the enzyme will be saturated with substrate. The rate of reaction does not increase anymore by increasing substrate concentration. Inhibition by chemical agents (inhibitors): reversible: can be reactivated.
