BIOL 3600 Lecture Notes - Lecture 21: Purine Metabolism, Pyrimidine Metabolism, Carbamoyl Phosphate
25 Apr 2020
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May finish before the end of monday, so we will move onto chapter 26 then. Hopes you can see how it integrates into _____________ metabolism. (4 minutes in) #2 nucleotides are made in both de novo and salvage pathways. De novo = latin for new , so in english made from scratch . We can stop in metabolism at any point and go in the opposite direction. We do this with nucleotides in our diet. We use it in both the salvage or the de novo pathways. Important to know what pprp is [phosphribosyl-pyrophosphate (prpp)] and that we can make them from new material or from catabolites. 2 different classes of nucleotides (not rna and dna), but these are classified by their bases: purines (a&g: more complex and larger) and pyrimidines (c, u & t : smaller, less complex nucleotides) #4 the de novo pathway for pyrimidine biosynthesis uses carbamoyl phosphate and aspartate. Carbamoyl phosphate 2nd time we"ve seen this.
