BIO 346 Lecture Notes - Lecture 8: Interquartile Range, Hmga2, Heritability
Document Summary
Heritability - traits passed down from parents to offspring. People who are more related to each other are on average more similar to each other (predates our understanding of dna and epigenetics) Some of the mathematical properties don"t match that that relates to genes inheritance. Discrete alleles convey discrete phenotypes mathematically related. 1886 - galton - linear regression - explain continuous variability. Quantified traits of parent and offspring - and see the relationship between traits (slope of the best fit line) 1918 - fisher - quantitative traits (i. e. height) - explained by particulate inheritance by particular loci. Each small bit contributes a bit more and more (phenotypes look continuous) 2007 - first segment of dna identified that contributes to common variation in height, hmga2. Relation between natural variation in height and natural variation in dna. How to put a number on how strong the effect is. Come up with a way to quantify variation (within a population)
