BIO 311C Lecture Notes - Lecture 21: Azide, Citric Acid Cycle, Atp Synthase

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11 Nov 2017
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Oxidation of nadh nad+ / fadh2 fad. Electrons released from oxidation are transferred to etc proteins i. ii: results in proton concentration gradient, chemiosmosis: h+ moving from high to low concentration v. Atp synthesis: adp + pi atp phosphorylation . Atp transported to cytoplasm via adp/atp translocate. *nad+ & fad return to acetyl coa formation & krebs cycle. Eventually to glycolysis via electron shuttle i. Uncouplers of [delta h]+ : make inner membrane leaky to ions. H+ don"t go through atp synthase, no atp made ex: dnp. Atp synthase inhibitors: antibiotics / ex: oligomyocin ii: et blockers: carbon monoxide, cyanide, azide.

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