BIO 353 Lecture Notes - Lecture 2: Sister Chromatids, Spindle Apparatus, G2 Phase

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13 Jun 2018
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Cell Cycle
Interphase
o S Phase
Synthesis, once the decision to divide has been made, all genetic
information in the cell is replicated/duplicated
o G2 Phase
Preparing/creating components for cell division
o Non dividing cell
Mitosis
o Prophase
Chromosome coil up and condense, centrioles divide and move apart
o Prometaphase
Chromosomes are clearly double structures; centrioles reach the opposite
poles; spindle fiber forms
o Metaphase
Centromeres align on metaphase plate
Nuclear envelope completely dissolved
Chromosomes, all 4, 2 homologous pairs, aligning independently at
metaphase plate
o Anaphase
Centromeres split and daughter chromosomes migrate to opposite poles
Sister chromatids separate
o Telophase
Daughter chromosomes arrive at the poles; cytokinesis commences
Spindle apparatus break down
Independent event; cytokinesis
G1
G0
o Never divide again
1 Chromosome, 2 sister chromatids
o Sister chromatids identical
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