HHP 3500 Lecture Notes - Lecture 29: Hematopoietic Stem Cell, Lymphoblast, Bone Marrow

• School: University of Iowa
• Department: Health and Human Physiology
• Course: HHP 3500
• Professor: Peterson Clayton

Document Summary

Formed elements are cells and cell fragments. Consist of erythrocytes (45% of blood) leukocytes, and platelets. Adults only make blood cells in vertebral column, pelvis, Erythrocytes (red blood cells) sternum, rib cage: formation: Stem cell turns into a myeloid progenitor cell, then if it differentiates to become a red blood cell, it has extrusion of nuclei and organelles (since red blood cells are denucleated and don"t have organelles, besides ribosomes) Once it gets rid of the organelles, it is called (cid:498)reticulocyte(cid:499) Reticulocytes then mature into red blood cells: structure: Small cells, biconcave disk shape (this shape maximizes surface area for carrying co2 and o2) Hemoglobin has 4 domains, with a heme group inside, that contains an fe. Males have slightly higher levels of hemoglobin. If we know hematocrit (% of red blood cells) and we know hemoglobin counts, we can determine your ability to carry oxygen- o2-carrying capacity: function: Transport oxygen and co2 throughout body: erythropoiesis-generation of new rbcs.