HHP 3500 Lecture Notes - Lecture 23: T Cell, Arteriole, Pulmonary Artery

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Lecture 23: structure and function of circulatory system. Single celled- organisms use diffusion as transportation. Multicellular organisms diffuse too slowly, must rely on bulk flow-all components move together throughout the body, and all cells are close access to blood. Path=substances are dissolved in plasma, and when they get to location, leave plasma, enter interstitial fluid and then enter cells-there is a flux throughout all of these areas to enable transportation: components: Blood is a type of connective tissue (it connects different areas via flow) Blood cells begin in bone marrow as multipotent stem cells-upon differentiation they can become blast cells (undifferentiated by can become mature cells) or lymphocyte precursor (eventually give rise to b and t lymphocytes) Composition: formed elements-cells and cell fragments. Erythrocytes-99% of blood composition- red blood cells, transport o2. Platelets-cell fragments, blood clotting: plasma volume-fluid contents. Substances dissolved in plasma volume (not formed elements), like proteins. 7% are proteins, which help generate osmotic pressure.

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