ADSC 3300 Lecture Notes - Lecture 12: Oxidative Phosphorylation, Reducing Equivalent, Pentose
19 Apr 2017
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Need to know about pathways: key enzymes, where it occurs, what starts with/ends with, and does it use or produce energy. **glucose-6-phosphate is a central compound to all the pathways we discussed. Glucose comes into the cell gets turned in to glucose 6 phosphate (could get turned in to glycogen then) or go to the pentose phosphate pathway. 2 nadph for every glucose that goes through. 1st key enzyme: glucose-6-phosphate dehydrogenase: takes hydroxyl and converts to carboxyl. 2nd key enzyme: 6-phosphoglucanate dehydrogenase: we make 2nd nadh and spontaneously co2 is lost. Lipid metabolism (last set of slides for semester) **fat in diet gets digested by pancreatic lipase and then gets absorbed and gets released as chylomicrons that can be passed around to different tissues such as muscle (adipose tissue) or the liver. Fat gets broken down into fatty acids (esterification). *overall reaction: 8 acetyl-coa + 7 atp (gets used in acetyl-coa carboxylase step) + 14.
