BISC300 Lecture Notes - Lecture 10: Bacteriocin, Natural Killer Cell, Microbiota
27 Nov 2016
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3 lines of defense: 1st: non specific- mechanical (peristalsis- more delayed reaction, diarrhea) and chemical (salvia) and reflexes (coughing, sneezing, 2nd: non specific: fever, protective proteins-cytokines, phagocytosis, nk cells, Inflammation; ~48 hours: 3rd: specific (acquired) immunity: cell-mediated, humoral; two weeks. First line of defense: physical barrier, chemical barrier, mechanical barrier, microbiome good gut bacteria. Normal flora protect against infection: competing with pathogenic microbes. Space and food: production antibacterial compound. Organs and tissues of immune system: primary organs and tissues. Sites where lymphocytes mature and differentiate into antigen-sensitive mature b and t cells: secondary organs and tissues. Areas where lymphocytes may encounter and bind antigen followed by proliferation and differentiation into fully mature effector cells. Can be caused by pathogen or physical trauma. Acute inflammation is the immediate response of body to injury or cell death: cardinal signs (acute) redness (rubor) Altered function (functio laesa)- loss of f(x)
